Specially designed to treat insect pests: caterpillars, moths, stink bugs, hanging wireworms, cabbage worms
Dilution ratio: 1:1000
Dilution method: 1000 liters/100 ml/2000 square meters/21528 square feet.
Cypermethrin is moderately toxic if it comes in contact with the skin or if swallowed. It may irritate the skin and eyes. Symptoms of skin contact include numbness, tingling, itching, burning sensation, loss of bladder control, loss of coordination, seizures, and possibly death.
Cypermethrin is a synthetic pyrethrin that is a fast-acting neurotoxin for insects. Cypermethrin is usually present as a yellow to amber viscous liquid. Although it is difficult to dissolve in water, it can be dissolved in organic solvents such as alcohols, chlorinated hydrocarbons, ketones, cyclohexane, benzene, xylene, etc. Although it is easily decomposed in soil and plants, it can remain on the surface of indoor environments for weeks. Although it is relatively stable to light and heat, sunlight, water, and oxygen will accelerate the decomposition of cypermethrin. It has contact and stomach poisoning effects, and its efficacy is higher than that of permethrin. It is suitable for insect repellent and insecticide, such as flies, mosquitoes, and blackflies. According to the National Pesticides Telecommunications Network (NPTN), cypermethrin is highly toxic to fish.
Animal studies
Cypermethrin is highly toxic to cats because they cannot tolerate the therapeutic doses used by dogs. This is related to the lack of UGT1A6 (the enzyme responsible for metabolizing cypermethrin) in cats. Therefore, cypermethrin remains in the body of cats for longer periods of time than in dogs or other mammals, and large doses can be fatal.
Studies by Elbetieha et al. (2001) showed that cypermethrin has toxic effects on the reproductive system of male rats. Another study showed that after 15 days of continuous administration, both androgen receptor levels and serum testosterone levels were significantly reduced. These data suggest that high doses of cypermethrin can cause damage to the structure of the seminiferous tubules and spermatogenesis in male rats.
Studies have found that long-term exposure to cypermethrin in adulthood can induce dopaminergic neurodegeneration in rats, and re-exposure after birth can enhance the sensitivity of animals to dopaminergic neurodegeneration.
If rats are exposed to cypermethrin during pregnancy, their offspring are developmentally retarded. Male rats exposed to cypermethrin had an increased percentage of abnormal sperm. Cypermethrin causes genetic damage: Mice exposed to cypermethrin had an increase in chromosomal abnormalities in bone marrow and spleen cells. Cypermethrin is listed as a potential human carcinogen because it causes an increased incidence of lung cancer in female mice. Cypermethrin has been associated with an increase in bone marrow micronuclei in mice and humans.
One study showed that cypermethrin inhibits "gap junctional communication," which plays an important role in cell growth and is inhibited by carcinogens. Studies have shown that residues of cypermethrin can persist in the air, walls, floors, and furniture for 84 days.
Cypermethrin is a broad-spectrum insecticide, meaning it kills not only target insects but also beneficial insects. Fish are particularly susceptible to cypermethrin, but when used as directed, cypermethrin use around residential areas poses little risk to aquatic life. Insects that are regularly exposed to cypermethrin quickly develop resistance to cypermethrin and may render it ineffective.
Environmental impacts and potential risks
Cypermethrin is a widely used insecticide that kills not only target insects but also beneficial insects. Fish are particularly susceptible, but spraying around residential areas poses little risk to aquatic life if used as directed. Insects that are regularly exposed to cypermethrin can quickly develop resistance, which may render its effectiveness ineffective.
Cypermethrin is highly toxic to cats, who are unable to tolerate canine doses of cypermethrin . This is because cats lack the glucuronidase enzyme needed to metabolize cypermethrin, allowing it to remain in the body for a longer period of time.
Human exposure
Cypermethrin is moderately toxic by skin contact or oral ingestion and is an irritant to the skin and eyes. Symptoms of skin exposure include numbness, tingling, itching, burning, loss of bladder control, movement disorders, seizures, and even death. Pyrethroids may have adverse effects on the central nervous system. Volunteers exposed to 130 μg/cm² on the earlobe experienced localized stinging and burning sensations. One man died after ingesting oil containing 10% cypermethrin, which he mistakenly used as cooking oil. Nausea, prolonged vomiting, stomach pain, and diarrhea occurred immediately after ingestion, followed by convulsions, loss of consciousness, and coma. Other family members had milder symptoms and survived after hospital treatment. Cypermethrin may cause allergic skin reactions. Overexposure can cause nausea, headache, decreased muscle strength, excessive salivation, difficulty breathing, and seizures. Cypermethrin is enzymatically hydrolyzed in the body to several carboxylic acid metabolites, which are inactive and excreted in the urine. Worker exposure can be monitored by measuring metabolites in urine, but severe overexposure can be confirmed by measuring concentrations in blood or plasma.
害虫駆除用として特別に設計されています：毛虫、蛾、カメムシ、ハリガネムシ、アオムシ
希釈率：1:1000
希釈方法：1000リットル/100ml/2000平方メートル/21528平方フィート
シペルメトリンは、昆虫に対して速効性のある神経毒である合成ピレトリンです。シペルメトリンは、通常、黄色から琥珀色の粘稠な液体です。水には溶けにくいですが、アルコール、塩素化炭化水素、ケトン、シクロヘキサン、ベンゼン、キシレンなどの有機溶媒には溶けます。土壌や植物では容易に分解されますが、室内環境の表面には数週間残留する可能性があります。光と熱に対しては比較的安定していますが、日光、水、酸素はシペルメトリンの分解を促進します。シペルメトリンは接触毒性および胃毒性を有し、その効力はペルメトリンよりも高い。ハエ、蚊、ブユなどの虫よけ・殺虫剤として適している。米国農薬情報通信ネットワーク（NPTN）によると、シペルメトリンは魚類に対して非常に毒性が高い。
環境への影響と潜在的リスク
シペルメトリンは広く使用されている殺虫剤で、標的昆虫だけでなく益虫も駆除する。魚類は特に感受性が高いが、指示通りに使用すれば住宅地周辺に散布しても水生生物へのリスクはほとんどない。シペルメトリンに定期的に曝露された昆虫はすぐに耐性を獲得し、その効果が失われる可能性がある。
シペルメトリンは猫にとって非常に毒性が高く、猫は犬と同じ量のシペルメトリンに耐えられない[3]。これは、猫がシペルメトリンの代謝に必要なグルクロニダーゼ酵素を欠損しているため、シペルメトリンが体内に長期間残留してしまうためである。
人体への曝露
シペルメトリンは、皮膚接触または経口摂取により中程度の毒性を示し、皮膚および眼を刺激します。皮膚曝露の症状には、しびれ、チクチク感、かゆみ、灼熱感、排尿コントロールの喪失、運動障害、発作、さらには死に至ることもあります。ピレスロイド系は中枢神経系に有害な影響を及ぼす可能性があります。被験者は耳たぶに130μg/cm²の濃度で曝露され、局所的な刺痛および灼熱感を経験しました。ある男性は、誤って食用油として使用し、シペルメトリン10%含有油を摂取した後に死亡しました。摂取直後に吐き気、長時間の嘔吐、腹痛、下痢が起こり、その後、痙攣、意識喪失、昏睡に陥りました。他の家族はより軽度の症状を呈し、入院治療により生存しました。シペルメトリンはアレルギー性皮膚反応を引き起こす可能性があります。過剰曝露は、吐き気、頭痛、筋力低下、唾液過多、呼吸困難、発作を引き起こす可能性があります。シペルメトリンは体内で酵素加水分解され、複数のカルボン酸代謝物に変換されます。これらの代謝物は不活性となり、尿中に排泄されます。作業者の曝露量は尿中の代謝物の測定によってモニタリングできますが、重度の過剰曝露は血中または血漿中の濃度を測定することで確認できます。
