Research by the International Atomic Energy Agency shows that if food is irradiated with cobalt-60 or cesium-137 gamma rays with an average dose of less than 60 kilogray (㏉), electron beams with an energy of 10 MeV, or X-rays produced by electron beams with an energy of less than 5 MeV, the increase in background radiation caused by human consumption of these irradiated foods is very small, and can be said to be close to zero.
Radiation safety vs microbiological safety vs toxicological safety
A research document from the Center for Food Safety revealed that during the irradiation process, food passes through the irradiation zone at a set speed to control the energy or radiation dose absorbed by the food. In a controlled environment, food does not come into direct contact with the radiation source. However, some studies have shown that ground beef or beef scraps can be detected to be induced radioactive after being irradiated with X-rays produced by 7.5 (㏉) electrons (although the report also explains that the risk to humans is extremely low).
Based on the experimental results of the World Health Organization, the Food and Agriculture Organization of the United Nations and the International Atomic Energy Agency, the Codex Alimentarius Commission has stipulated that the maximum radiation absorbed dose of food should not exceed 10 kilograys (㏉) (Gy) (English: Gray, abbreviated symbol: ㏉, translated as "戈瑞" in mainland China, translated as "戈雷" in Taiwan; also translated as "格雷"), abbreviated as "Gy, is an International System of Units derived unit and the standard unit of the physical quantity "ionizing radiation energy absorbed dose". It is mainly used in the field of medicine to describe the radiation dose used in radiotherapy and nuclear medicine.), and the maximum energy levels of X-rays and electrons generated by mechanical sources are set at 5 MeV and 10 MeV respectively. One of the reasons for setting this limit level is to avoid induced radioactivity in irradiated food.
Another topic is microbial safety. Since it was discovered many years ago that ionizing radiation can induce mutations, the issue of radiation mutation has attracted much attention. Experiments have shown that multiple rounds of irradiation of cultured bacteria can induce the emergence of radiation-resistant microbial communities. After bacteria and other microorganisms mutate, scientific research has not yet been able to determine whether the toxicity or pathogenicity of the new bacteria may be stronger or weaker than the parent bacteria, or it may be similar to the parent bacteria. Although irradiated food may theoretically lead to the emergence of new pathogens.
Finally, in toxicology, we have historically relied on feeding tests in animals for toxicity studies (including rats, mice, dogs, quail, hamsters, chickens, pigs, and monkeys). Several generations of experimental animals were fed with irradiated foods at doses ranging from 25 to 50 kGy (much higher than the dose used to irradiate human diets). These animals did not develop genetic mutations, deformities or tumors as a result of eating irradiated foods. Although the International Atomic Energy Agency concluded in 1980 that any food irradiated with a dose below 10 kilogray (㏉) would not cause toxicological hazards.
However, relatively few trials have been conducted in humans, and most of the research has been conducted by the US military. These clinical studies evaluated the subjects' heart, blood, liver and kidney function and were all short-term in nature. Within one year after the trial, no clinical abnormalities were found in the subjects.
One of the most well-known human dietary trials was conducted in 1975, in which 15 malnourished Indian children were fed a diet containing irradiated wheat (at a dose of 0.75 kGy). During the trial, the children's polyploidy frequency and number of abnormal cells were found to increase, but after they stopped eating the irradiated diet, the abnormal cells returned to baseline levels. The authors of the research report believe that the above situation is caused by eating irradiated food. However, if we read the report carefully, we will know that the research only calculated 100 cells in each of the five children in each group. Based on such a small sample size, it is not possible to draw conclusions.
In addition, some people point out that it usually takes decades to prove whether food is carcinogenic, and all current animal studies are too short to reveal the carcinogenicity of irradiated food.
Irradiation of food produces carcinogen 2-alkylcyclobutanone
During the irradiation process, radiation decomposes triglycerides in fat-containing foods to produce a group of molecules, namely 2-alkylcyclobutanone. 52 2-Alkylcyclobutanones have been found only in irradiated fat-containing foods and not in non-irradiated foods that have been processed by other methods. Therefore, this compound is considered unique to irradiated foods. This suggests that 2-alkylcyclobutanones present only in irradiated fat-containing foods may make animals injected with chemical carcinogens more susceptible to colon cancer, but also shows that 2-alkylcyclobutanones alone do not cause colon cancer. However, it is worth noting that the dose of 2-alkylcyclobutanone used in this study was much higher than the amount of 2-alkylcyclobutanone a person would consume from a daily diet containing irradiated food.